Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27546100 | 0.97 | — | — | |
| Bicarbonate SCHEMBL27864074 | 0.88 | TP53 (0.38) | — | |
| SCHEMBL10549230 | 0.78 | — | — | |
| SCHEMBL844187 | 0.76 | — | — | |
| SCHEMBL6573417 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL1980632 | 0.75 | — | — | |
| SCHEMBL10484240 | 0.75 | ALDH1A1 (0.35) | — | |
| Nitric Acid SCHEMBL7573949 | 0.73 | CA5A (0.57) | — | |
| SCHEMBL2286647 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL1446238 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109674679-A | A kind of skin barrier maintenance biomembrane and preparation method thereof | 贝德氏（上海）健康科技股份有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109568216-A | A kind of skin barrier maintenance Mu Lu and preparation method thereof | 贝德氏（上海）健康科技股份有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-108449995-A | representative diagnosis | 文塔纳医疗系统公司 | 2018-08-24 | — | — | CN | claimed |
| CN-109688831-A | Feed addictive comprising allicin | 奥姆尼根研究有限责任公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-104755582-B | For stimulating the method and composition for producing hydro carbons from subsurface formations | 弗洛泰克化学有限责任公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-109181671-A | Mobility for improving oil recovery controls polymer | 艺康美国股份有限公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-104829720-B | KIR-BINDING AGENTS AND METHODS OF USING THE SAME | 诺和诺德公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-108587590-A | For stimulating the method and composition for producing hydro carbons from subsurface formations | 弗洛泰克化学有限责任公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108368125-A | Acc inhibitors and uses thereof | 吉利德阿波罗公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-108349995-A | Pyrazoles ACC inhibitor and application thereof | 吉利德阿波罗公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-108349994-A | Triazole ACC inhibitor and application thereof | 吉利德阿波罗公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-108348453-A | Including the antimicrobial compositions of mupirocin and neomycin | 罗切斯特大学 | 2018-07-31 | — | — | CN | disclosed |
| CN-108290902-A | Esters ACC inhibitor and application thereof | 吉利德阿波罗公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-108289479-A | Composition for aquaculture and/or combination | 奥姆尼根研究有限责任公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-106413717-A | Pharmaceutical compositions | 查尔斯顿实验室公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-105849099-A | Polycyclic inhibitors of cyclin-dependent kinase 7 (CDK7) | 达纳-法伯癌症研究所股份有限公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-103261362-B | Treating illite formations with chelating agents | 阿克佐诺贝尔化学国际公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-105797140-A | Stable formulations of an acetyl hyaluronan-degrading enzyme | 哈洛齐梅公司 | 2016-07-27 | — | — | CN | disclosed |