SCHEMBL2286647

SCHEMBL2286647

O=[N+]([O-])C(O)C(O)C(O)[N+](=O)[O-]

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
HIF1A Q16665 1/20 0.39
CA5A P35218 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435820 0.78 LMNA (0.48) ALDH1A1
SCHEMBL10549230 0.76
SCHEMBL8753950 0.76 ALDH1A1 (0.37) ALDH1A1HPGDHIF1ACA5ACA5B
SCHEMBL9344039 0.76 ALDH1A1 (0.40) ALDH1A1HPGDHIF1ACA5ACA5B
SCHEMBL844187 0.74
SCHEMBL6235669 0.73
SCHEMBL11045907 0.73 ALDH1A1 (0.35) ALDH1A1HPGDHIF1ACA5ACA5B
SCHEMBL11287208 0.73
SCHEMBL6573417 0.73 ALDH1A1 (0.35) ALDH1A1HPGDHIF1ACA5ACA5B
SCHEMBL3594959 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270178-A1 METHODS OF PRODUCING A NITRATE ESTER NORTHROP GRUMMAN SYSTEMS CORPORATION 2025-08-28 US claimed
US-20230183198-A1 METHODS OF PRODUCING GLYCIDYL NITRATE AND RELATED SYSTEMS NORTHROP GRUMMAN SYSTEMS CORPORATION 2023-06-15 US claimed
CN-114585356-A Methods of preventing or treating diseases associated with VEGFR and/or VEGF inhibition 上海岸阔医药科技有限公司 2022-06-03 CN claimed
WO-2021073535-A1 METHOD FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH ADMINISTRATION OF VEGFR AND/OR VEGF INHIBITOR 上海岸阔医药科技有限公司 2021-04-22 WO claimed
US-10562873-B1 Methods of producing glycidyl nitrate Northrop Grumman Innovation Systems, Inc. (US) 2020-02-18 US claimed
US-7539006-B2 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2009-05-26 US claimed
US-20070029529-A1 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor KOMATSU AKIHIKO 2007-02-08 US claimed
US-6870061-B2 Continuous process and system for production of glycidyl nitrate from glycerin, nitric acid and caustic and conversion of glycidyl nitrate to poly(glycidyl nitrate) ALLIANT TECHSYSTEMS INC. (US) 2005-03-22 US claimed
EP-1240234-B1 POLYMERIZATION OF POLY(GLYCIDYL NITRATE) FROM HIGH PURITY GLYCIDYL NITRATE SYNTHESIZED FROM GLYCEROL ALLIANT TECHSYSTEMS INC (US) 2004-12-29 EP claimed
US-20040245105-A1 Electrolyte solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2004-12-09 US claimed
US-20040138481-A1 Continuous process and system for production of glycidyl nitrate from glycerin, nitric acid and caustic and conversion of glycidyl nitrate to poly(glycidyl nitrate) NORTHROP GRUMMAN SYSTEMS CORPORATION 2004-07-15 US claimed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 EP claimed
EP-1240234-A1 POLYMERIZATION OF POLY(GLYCIDYL NITRATE) FROM HIGH PURITY GLYCIDYL NITRATE SYNTHESIZED FROM GLYCEROL ALLIANT TECHSYSTEMS INC. (US) 2002-09-18 EP claimed
US-6362311-B1 NITRATING GLYCEROL; POLYMERIZATION ALLIANT TECHSYSTEMS INC. 2002-03-26 US claimed
WO-2001029111-A1 POLYMERIZATION OF POLY(GLYCIDYL NITRATE) FROM HIGH PURITY GLYCIDYL NITRATE SYNTHESIZED FROM GLYCEROL ALLIANT TECHSYSTEMS INC. (US) 2001-04-26 WO claimed
US-4415456-A Removal and destruction of residual nitrate esters in wastewater HERCULES INCORPORATED (US) 1983-11-15 US claimed
US-20250270178-A1 METHODS OF PRODUCING A NITRATE ESTER NORTHROP GRUMMAN SYSTEMS CORPORATION 2025-08-28 US disclosed
US-20240415795-A1 TOPICAL FORMULATIONS OF NITROGLYCERIN PERMEATUS, INC. 2024-12-19 US disclosed
US-4415456-A Removal and destruction of residual nitrate esters in wastewater HERCULES INCORPORATED (US) 1983-11-15 US disclosed
US-4318270-A Additives for suppressing the radar attenuation of rocket propellant exhaust plumes THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1982-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10562873-B1 Methods of producing glycidyl nitrate GMPS, GK, GAPDH ALDH1A1 968/4885HPGD 11/4885HIF1A 2015/4885
US-20230183198-A1 METHODS OF PRODUCING GLYCIDYL NITRATE AND RELATED SYSTEMS GMPS, PTGIS, GK ALDH1A1 3028/4885HPGD 21/4885HIF1A 2297/4885
US-20250270178-A1 METHODS OF PRODUCING A NITRATE ESTER NOS2, NOS3, NOS1 ALDH1A1 389/4885HPGD 96/4885HIF1A 2579/4885
US-20040138481-A1 Continuous process and system for production of glycidyl nitrate from glycerin, nitric acid and caustic and conversion of glycidyl nitrate to poly(glycidyl nitrate) GMNN, GLMN, GMPS ALDH1A1 1887/4885HPGD 187/4885HIF1A 1954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.