Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
| ▸ | ATP4B | P51164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705317 | 0.91 | CYP2D6 (0.37) | SMN1; SMN2NPC1RAB9AHSD17B10TDP1 | |
| SCHEMBL28062722 | 0.89 | SMN1; SMN2 (0.33) | SMN1; SMN2NPC1RAB9AHSD17B10POLB | |
| SCHEMBL28062734 | 0.88 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1RAB9AHSD17B10POLB | |
| SCHEMBL17937758 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9AHSD17B10POLB | |
| SCHEMBL28062819 | 0.82 | MGLL (0.36) | SMN1; SMN2NPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL17937618 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9AHSD17B10POLB | |
| SCHEMBL706387 | 0.81 | LTA4H (0.44) | ALDH1A1TDP1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL28827544 | 0.81 | POLB (0.35) | SMN1; SMN2POLBALDH1A1TDP1P2RX7 | |
| SCHEMBL28827525 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9AHSD17B10POLB | |
| SCHEMBL28062721 | 0.80 | KMT2A (0.42) | SMN1; SMN2NPC1RAB9AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555901-A | Polishing composition | FUJIMI INC | 2016-05-04 | — | — | CN | disclosed |