SCHEMBL28062839

SCHEMBL28062839

CCCO[Si](C)(OCCC)c1ccc(Cl)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 4/20 0.33
LMNA P02545 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
POLB P06746 2/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
GCGR P47871 2/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705703 0.89 ESR1 (0.31) ALDH1A1KDM4EHPGDSMN1; SMN2NPC1
SCHEMBL28062854 0.89 POLB (0.40) ALDH1A1SMN1; SMN2NPC1RAB9APOLB
SCHEMBL28062710 0.83 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDSMN1; SMN2LMNA
SCHEMBL3482147 0.82 ACHE (0.33) ALDH1A1POLBTDP1
SCHEMBL17529776 0.82 SMN1; SMN2 (0.34) ALDH1A1KDM4EHPGDSMN1; SMN2LMNA
SCHEMBL9804106 0.80 MAPT (0.38) ALDH1A1KDM4ELMNANPC1RAB9A
SCHEMBL19809191 0.80 ESR1 (0.47) ALDH1A1KDM4ESMN1; SMN2LMNANPSR1
SCHEMBL3481566 0.80 TP53 (0.34) ALDH1A1KDM4EHPGDSMN1; SMN2LMNA
SCHEMBL28062851 0.80 MAPT (0.33) ALDH1A1KDM4EHPGDSMN1; SMN2LMNA
SCHEMBL426599 0.79 LMNA (0.38) ALDH1A1HPGDSMN1; SMN2LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555901-A Polishing composition FUJIMI INC 2016-05-04 CN disclosed