Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 6/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28062756 | 0.90 | HIF1A (0.41) | ALOX5ELANEDHODHPOLBKCNQ3 | |
| SCHEMBL28062885 | 0.80 | EGFR (0.46) | PIM1 | |
| SCHEMBL21430571 | 0.80 | POLB (0.48) | ALOX5ELANEPOLBHTTKDM4E | |
| SCHEMBL5241382 | 0.77 | EGFR (0.48) | HTTKDM4EGAAHSD17B10 | |
| SCHEMBL17469272 | 0.76 | MAPT (0.45) | POLBHTTKDM4EGAAHSD17B10 | |
| SCHEMBL7490158 | 0.76 | EGFR (0.58) | POLBHTTKDM4E | |
| SCHEMBL15473666 | 0.73 | HIF1A (0.49) | — | |
| SCHEMBL10253811 | 0.71 | KDM4E (0.69) | KCNQ3KCNQ2KDM4EGAAHSD17B10 | |
| SCHEMBL9287885 | 0.71 | KDM4E (0.43) | ALOX5ELANEKCNQ3KCNQ2KDM4E | |
| SCHEMBL28062862 | 0.71 | ENPP2 (0.43) | GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646327-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |