Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469278 | 0.82 | KDM4E (0.44) | MAPTSMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL17469273 | 0.82 | POLB (0.46) | MAPTSMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL24236616 | 0.79 | PLA2G2A (0.58) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL17469277 | 0.78 | KMT2A (0.40) | ALDH1A1CYP1A2CYP2C19HTTMEN1 | |
| SCHEMBL17469290 | 0.78 | KMT2A (0.42) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL5241382 | 0.77 | EGFR (0.48) | SMN1; SMN2ALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL17469291 | 0.77 | KMT2A (0.56) | MAPTSMN1; SMN2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL17469283 | 0.77 | MEN1 (0.39) | ALDH1A1MEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL17469287 | 0.77 | KMT2A (0.39) | ALDH1A1HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL28062874 | 0.76 | ALOX5 (0.43) | KDM4EHSD17B10HTTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016014426-A1 | ORGANIC REACTIONS | THE ARIZONA BOARD OF REGENTS (US) | 2016-01-28 | — | — | WO | disclosed |