Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 13/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28062767 | 0.89 | EGFR (0.44) | EGFROXER1GFERBAZ2B | |
| SCHEMBL28062862 | 0.89 | ENPP2 (0.43) | OXER1 | |
| SCHEMBL28062874 | 0.80 | ALOX5 (0.43) | PIM1 | |
| SCHEMBL7490158 | 0.79 | EGFR (0.58) | EGFR | |
| SCHEMBL29364893 | 0.75 | OXER1 (0.58) | EGFROXER1 | |
| SCHEMBL18357899 | 0.75 | OXER1 (0.58) | EGFROXER1 | |
| SCHEMBL8899162 | 0.72 | CYP11B1 (0.40) | EGFROXER1DYRK3PIM1MAPK8 | |
| SCHEMBL11372872 | 0.72 | GSK3B (0.57) | EGFR | |
| SCHEMBL14848284 | 0.72 | EGFR (0.47) | EGFROXER1GFER | |
| SCHEMBL5241382 | 0.72 | EGFR (0.48) | EGFRDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646327-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |