Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.47 |
| ▸ | HTR3A | P46098 | 8/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600790 | 0.73 | HRH3 (0.49) | HTR3ACYP3A4CYP2D6CYP2C9SLC6A4 | |
| SCHEMBL1600792 | 0.73 | HRH3 (0.49) | HTR3ACYP3A4CYP2D6CYP2C9SLC6A4 | |
| SCHEMBL4282739 | 0.71 | SLC6A4 (0.42) | HTR1ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2246688 | 0.70 | PLG (0.45) | HTR1ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7501787 | 0.70 | LTA4H (0.41) | HTR1ACYP2D6SLC6A4LTA4HSLC6A2 | |
| SCHEMBL27600947 | 0.70 | LTA4H (0.41) | CYP2D6SLC6A4ALDH1A1LTA4HSLC6A2 | |
| SCHEMBL3824584 | 0.70 | NOS3 (0.35) | HTR1ASLC6A4LTA4HSLC6A2SLC6A3 | |
| SCHEMBL11705626 | 0.69 | SLC6A4 (0.65) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1191610 | 0.68 | SLC6A4 (0.63) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13241649 | 0.68 | SLC6A4 (0.68) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110022869-A | For skin and/or the serotonin 1B receptor stimulators of hair reparation | 巴斯德研究院 | 2019-07-16 | — | — | CN | disclosed |
| CN-108348486-A | 5-hydroxytryptamine 1B receptor agonists as promoters for satellite cell self-renewal and/or differentiation | 巴斯德研究院 | 2018-07-31 | — | — | CN | disclosed |
| CN-106083762-A | Fertile a kind of preparation method for western spit of fland intermediate | 北京万全德众医药生物技术有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105622546-A | Preparation method for vortioxetine | MAGUS PHARMACEUTICAL (XIAMEN) CO LTD | 2016-06-01 | — | — | CN | disclosed |