Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 7/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1440181 | 0.85 | AHR (0.61) | GPR84AHRTRPA1CA1CA2 | |
| SCHEMBL30071614 | 0.85 | AHR (0.61) | GPR84AHRTRPA1CA1CA2 | |
| Hydrochloric Acid SCHEMBL7763064 | 0.83 | AHR (0.58) | GPR84AHRTRPA1CA1CA2 | |
| Bromide SCHEMBL7762976 | 0.83 | AHR (0.58) | GPR84AHRTRPA1CA1CA2 | |
| SCHEMBL9729303 | 0.82 | PIK3CD (0.40) | GPR84AHRTRPA1CA1CA2 | |
| Hydrochloric Acid SCHEMBL11172742 | 0.81 | PIK3CD (0.39) | GPR84AHRTRPA1CA1CA2 | |
| SCHEMBL6151694 | 0.79 | ALDH1A1 (0.50) | GPR84AHRTRPA1CA1CA2 | |
| SCHEMBL23714123 | 0.76 | GPR84 (0.61) | GPR84AHRTRPA1CA1CA2 | |
| SCHEMBL2530865 | 0.75 | GPR84 (0.67) | GPR84AHRTRPA1CA1CA2 | |
| SCHEMBL3731175 | 0.73 | GPR84 (0.64) | GPR84AHRTRPA1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421105-B1 | ANTI-CANCER CYCLOPENTA¬G QUINAZOLINE COMPOUNDS | BTG INT LTD (GB) | 2010-10-06 | — | — | EP | disclosed |