SCHEMBL28063129

SCHEMBL28063129

COC(=O)c1ccc2[nH]c3ccc(C(=O)OC)cc3c2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.70
KDM4E B2RXH2 2/20 0.69
ALDH1A1 P00352 2/20 0.69
HPGD P15428 1/20 0.69
HSD17B10 Q99714 1/20 0.69
MEN1 O00255 5/20 0.68
KMT2A Q03164 5/20 0.68
RAB9A P51151 3/20 0.65
NPC1 O15118 1/20 0.65
ATM Q13315 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
HCRTR1 O43613 1/20 0.58
MAPT P10636 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
CREBBP Q92793 1/20 0.57
PSMB8 P28062 1/20 0.55
GABRA1 P14867 1/20 0.55
GABRG2 P18507 1/20 0.55
GABRB3 P28472 1/20 0.55
GABRA3 P34903 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71508 0.92 KIF11 (0.82) KIF11KDM4EALDH1A1HPGDHSD17B10
SCHEMBL29373898 0.90 KDM4E (0.66) KIF11KDM4EALDH1A1HPGDHSD17B10
SCHEMBL19331068 0.90 KDM4E (0.66) KIF11KDM4EALDH1A1HPGDHSD17B10
Clausine C SCHEMBL601713 0.86 KIF11 (0.67) KIF11KDM4EALDH1A1HPGDHSD17B10
SCHEMBL4725998 0.85 KIF11 (0.84) KIF11KDM4EALDH1A1HPGDHSD17B10
SCHEMBL29708168 0.85 KIF11 (0.84) KIF11KDM4EALDH1A1HPGDHSD17B10
SCHEMBL18941101 0.84 HCRTR1 (0.73) KIF11KDM4EALDH1A1HPGDHSD17B10
SCHEMBL26119516 0.84 KIF11 (0.71) KIF11KDM4EALDH1A1HPGDHSD17B10
SCHEMBL600063 0.84 KIF11 (0.64) KIF11KDM4EALDH1A1HPGDHSD17B10
SCHEMBL13780270 0.83 KDM4E (0.62) KIF11KDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534605-A Axis chiral thermal activation delayed luminescent material and preparation method and application thereof 中国科学院化学研究所 2024-02-09 CN disclosed
CN-105523992-A General synthetic method for N-substituted carbazole dicarboxylic acid derivatives SHANGHAI MASHILABS (CHEMICAL) CO LTD 2016-04-27 CN disclosed