SCHEMBL2806315

SCHEMBL2806315

CCO[Si](Cc1ccccc1)(Cc1ccccc1)OCC

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.44
TSHR P16473 3/20 0.37
SLC6A2 P23975 2/20 0.37
TAAR1 Q96RJ0 2/20 0.37
MAOA P21397 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
CYP2A6 P11509 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
CALM1 P0DP23 1/20 0.36
RELA Q04206 1/20 0.35
ALDH1A1 P00352 3/20 0.34
IDO1 P14902 2/20 0.34
LTA4H P09960 2/20 0.34
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL534257 0.93 TP53 (0.42) TP53TSHRCALM1RELAALDH1A1
SCHEMBL19809302 0.90 TP53 (0.37) TP53TSHRSLC6A2TAAR1MAOA
SCHEMBL19809283 0.90 TP53 (0.39) TP53TSHRCALM1RELAALDH1A1
SCHEMBL3341512 0.88 TP53 (0.38) TP53TSHRCALM1RELAALDH1A1
SCHEMBL19809224 0.88 TP53 (0.38) TP53TSHRCALM1RELAALDH1A1
SCHEMBL15302043 0.88 TP53 (0.38) TP53TSHRSIGMAR1CALM1RELA
SCHEMBL19816753 0.86 LTA4H (0.37) TP53TSHRRELALTA4H
SCHEMBL10439101 0.86 TP53 (0.37) TP53TSHRTAAR1SIGMAR1CALM1
SCHEMBL28426185 0.85 TP53 (0.35) TP53TSHRRELAALDH1A1
SCHEMBL19809210 0.85 TP53 (0.35) TP53TSHRALDH1A1LTA4HTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3986366-B1 COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE, AT LEAST ONE NON-AMINO SILICONE AND WATER, THE ALKOXYSILANE/NON-AMINO SILICONE MASS RATIO RANGING FROM 95/5 TO 5/95 OREAL (FR) 2024-09-11 EP claimed
CN-114007576-B Anhydrous composition comprising at least one aminosilicone, at least one alkoxysilane and at least one colorant 莱雅公司 2023-12-01 CN claimed
US-20220331228-A1 ANHYDROUS COMPOSITION COMPRISING AT LEAST ONE AMINO SILICONE, AT LEAST ONE ALKOXYSILANE AND AT LEAST ONE COLORING AGENT L'OREAL (FR) 2022-10-20 US claimed
EP-3986361-A1 ANHYDROUS COMPOSITION COMPRISING AT LEAST ONE AMINO SILICONE, AT LEAST ONE ALKOXYSILANE AND AT LEAST ONE COLORING AGENT L'OREAL (FR) 2022-04-27 EP claimed
EP-3986366-A1 COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE, AT LEAST ONE NON-AMINO SILICONE AND WATER, THE ALKOXYSILANE/NON-AMINO SILICONE MASS RATIO RANGING FROM 95/5 TO 5/95 L'OREAL (FR) 2022-04-27 EP claimed
CN-114007576-A Anhydrous composition comprising at least one aminosilicone, at least one alkoxysilane and at least one colorant 莱雅公司 2022-02-01 CN claimed
CN-113698437-A Sulfonate group ferrocene derivative and synthetic method and application thereof 中盐金坛盐化有限责任公司 2021-11-26 CN claimed
WO-2021214053-A1 PROCESS FOR DENSIFYING KERATIN FIBERS, BASED ON SILICONE, AN ALKOXYSILANE AND A COLORING AGENT L'OREAL (FR) 2021-10-28 WO claimed
US-11059920-B2 Process for producing high cis-1,4-polydiene with lanthanide-based catalyst compositions BRIDGESTONE CORPORATION (JP) 2021-07-13 US claimed
WO-2020260273-A1 COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE, AT LEAST ONE NON-AMINO SILICONE AND WATER, THE ALKOXYSILANE/NON-AMINO SILICONE MASS RATIO RANGING FROM 95/5 TO 5/95 L'OREAL (FR) 2020-12-30 WO claimed
EP-3491030-A1 PROCESS FOR PRODUCING HIGH CIS-1,4-POLYDIENE WITH LANTHANIDE-BASED CATALYST COMPOSITIONS Bridgestone Corporation (JP) 2019-06-05 EP claimed
CN-109715680-A The method for preparing high-cis -1,4- polydiene with the carbon monoxide-olefin polymeric based on lanthanide series 株式会社普利司通 2019-05-03 CN claimed
WO-2018022994-A1 PROCESS FOR PRODUCING HIGH CIS-1,4-POLYDIENE WITH LANTHANIDE-BASED CATALYST COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2018-02-01 WO claimed
CN-104302272-A Cosmetic composition comprising at least one alkoxysilane OREAL 2015-01-21 CN claimed
US-20140314696-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE L'OREAL (FR) 2014-10-23 US claimed
EP-2776004-A2 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE L'OREAL (FR) 2014-09-17 EP claimed
WO-2013068979-A2 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE L'OREAL (FR) 2013-05-16 WO claimed
US-7582712-B1 Alpha-olefins polymerization catalyst FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2009-09-01 US claimed
US-7307036-B2 Highly active alpha-olefin polymerization catalyst FORMOSA PLASTICS CORPORATION U.S.A. (US) 2007-12-11 US claimed
US-20060019821-A1 Highly active alpha-olefin polymerization catalyst FORMOSA PLASTICS CORPORATION, U.S.A. 2006-01-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220331228-A1 ANHYDROUS COMPOSITION COMPRISING AT LEAST ONE AMINO SILICONE, AT LEAST ONE ALKOXYSILANE AND AT LEAST ONE COLORING AGENT KRT18, SHH, VIM TP53 978/4885TSHR 4502/4885SLC6A2 3277/4885
US-20140314696-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE YWHAZ, SCO2, PRKCZ TP53 463/4885TSHR 3737/4885SLC6A2 3589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.