SCHEMBL28063170

SCHEMBL28063170

O=P(O)(O)c1cc(S(=O)(=O)c2ccc(Cl)c(P(=O)(O)O)c2)ccc1Cl.[NaH].[NaH]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
MAPK1 P28482 2/20 0.39
CYP3A4 P08684 1/20 0.39
SLC16A1 P53985 1/20 0.38
LMNA P02545 3/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 3/20 0.36
GAA P10253 2/20 0.36
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
FLT1 P17948 2/20 0.35
FLT4 P35916 2/20 0.35
KDR P35968 2/20 0.35
BCL2L1 Q07817 1/20 0.35
BCL2 P10415 1/20 0.35
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
FDPS P14324 1/20 0.34
CA12 O43570 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4350656 0.74 TSHR (0.44) ALDH1A1CYP3A4POLBMAPTSMN1; SMN2
SCHEMBL2870793 0.71 POLB (0.44) ALDH1A1MAPK1CYP3A4SLC16A1LMNA
SCHEMBL124383 0.71 POLB (0.44) ALDH1A1MAPK1CYP3A4SLC16A1LMNA
SCHEMBL2679084 0.71 MAPT (0.54) ALDH1A1MAPK1CYP3A4LMNAMAPT
SCHEMBL30343460 0.71 MAPT (0.54) ALDH1A1MAPK1CYP3A4LMNAMAPT
SCHEMBL5153928 0.70 GAA (0.52) ALDH1A1MAPK1CYP3A4SLC16A1LMNA
SCHEMBL3395636 0.69 LMNA (0.39) LMNAMAPTGAASMN1; SMN2KMT2A
SCHEMBL6008968 0.68 POLB (0.46) ALDH1A1MAPK1CYP3A4SLC16A1LMNA
SCHEMBL30534511 0.68 POLB (0.46) ALDH1A1MAPK1CYP3A4SLC16A1LMNA
SCHEMBL251503 0.68 POLB (0.46) ALDH1A1MAPK1CYP3A4SLC16A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105524267-A Random polymers with framework containing ammonium and phosphonic acid groups, and preparation method thereof UNIV TIANJIN 2016-04-27 CN disclosed