SCHEMBL4350656

SCHEMBL4350656

O=P(O)(O)c1cc(Cl)ccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP3A4 P08684 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TP53 P04637 3/20 0.44
GGPS1 O95749 1/20 0.43
CA1 P00915 1/20 0.43
CA14 Q9ULX7 1/20 0.43
FDPS P14324 1/20 0.39
CASP1 P29466 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11651153 0.83 TSHR (0.41) TSHRALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL28465322 0.78 TSHR (0.48) TSHRALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL3395636 0.77 LMNA (0.39) TSHRFDPSSMN1; SMN2MEN1KMT2A
Nitrogen SCHEMBL28466278 0.75 TSHR (0.45) TSHRALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL10800047 0.74 ALDH1A1 (0.48) TSHRALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL28063170 0.74 ALDH1A1 (0.39) ALDH1A1CYP3A4CA14FDPSSMN1; SMN2
SCHEMBL20379765 0.73 MMP1 (0.41) GGPS1CA1CA14FDPSSMN1; SMN2
Phosphoric Acid SCHEMBL28200084 0.73 TP53 (0.64) TSHRALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL11118429 0.72 MAPK1 (0.56) TSHRALDH1A1CYP3A4TDP1SMN1; SMN2
SCHEMBL20379820 0.71 FDPS (0.36) TSHRALDH1A1HSD17B10CYP3A4FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed
US-5861107-A ESTER INTERCHANGE OF 1,3-PROPANEDIOL COMPOUNDS WITH CARBONIC ACID ESTERS; DISTILLATIVE DEPOLYMERIZATION; CATALYSIS WITH TITANIUM OR ZIRCONIUM COMPOUND; PHOSPHORUS OR SULFUR COMPOUND STABILIZER BAYER AKTIENGESELLSCHAFT (DE) 1999-01-19 US disclosed
EP-0816354-A1 Process for preparing and stabilisation of aliphatic six-membered cyclic carbonates BAYER AG (DE) 1998-01-07 EP disclosed