Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28063243 | 0.87 | MTNR1A (0.41) | LMNAALDH1A1HPGDSMN1; SMN2MTNR1A | |
| Acetic Acid Methyl Ester SCHEMBL23070551 | 0.80 | CYP2C19 (0.53) | LMNAALDH1A1HPGDSMN1; SMN2CYP2C19 | |
| Acetone SCHEMBL27517311 | 0.80 | CYP2C19 (0.61) | LMNAALDH1A1HPGDSMN1; SMN2CYP2C19 | |
| Acetic Acid SCHEMBL23070491 | 0.80 | CYP2C19 (0.61) | LMNAALDH1A1HPGDSMN1; SMN2CYP2C19 | |
| SCHEMBL28121203 | 0.79 | CYP2C19 (0.49) | LMNAALDH1A1HPGDSMN1; SMN2CYP2C19 | |
| SCHEMBL17468450 | 0.78 | ALDH1A1 (0.69) | LMNAALDH1A1HPGDSMN1; SMN2CYP2C19 | |
| SCHEMBL28067208 | 0.78 | CYP2C19 (0.47) | LMNAALDH1A1HPGDSMN1; SMN2CYP2C19 | |
| Acetic Acid SCHEMBL28532080 | 0.74 | CYP2C19 (0.55) | LMNAALDH1A1HPGDSMN1; SMN2CYP2C19 | |
| Methyl Alcohol SCHEMBL29261078 | 0.73 | CYP2C19 (0.56) | LMNAALDH1A1HPGDSMN1; SMN2CYP2C19 | |
| SCHEMBL9104 | 0.73 | KDM4E (0.46) | ALDH1A1SMN1; SMN2KDM4EMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106148362-A | Novel coelenterazine substrates and methods of use thereof | 普罗梅加公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-103370319-B | Novel coelenterazine substrate and using method thereof | 普罗美加公司 | 2016-08-24 | — | — | CN | disclosed |