Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28063242 | 0.87 | LMNA (0.46) | MTNR1AMTNR1BL3MBTL1ALDH1A1HPGD | |
| Acetic Acid Methyl Ester SCHEMBL28504359 | 0.82 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1CYP2C9LMNA | |
| SCHEMBL28121204 | 0.81 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1 | |
| SCHEMBL28067210 | 0.79 | LMNA (0.41) | L3MBTL1ALDH1A1HPGDSMN1; SMN2LMNA | |
| Acetic Acid SCHEMBL28536489 | 0.78 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1SMN1; SMN2CYP2C9LMNA | |
| SCHEMBL8450 | 0.75 | IDO1 (0.44) | CA12CA1CA2CA9 | |
| Water SCHEMBL28337532 | 0.73 | IDO1 (0.43) | CA12CA1CA2CA9 | |
| SCHEMBL10519643 | 0.71 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1LMNA | |
| Acetic Acid SCHEMBL28365922 | 0.71 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9104 | 0.71 | KDM4E (0.46) | MTNR1AMTNR1BL3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106148362-A | Novel coelenterazine substrates and methods of use thereof | 普罗梅加公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-103370319-B | Novel coelenterazine substrate and using method thereof | 普罗美加公司 | 2016-08-24 | — | — | CN | disclosed |