Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27548526 | 0.80 | TSHR (0.58) | TDP1MAPTMAPK1RORCTSHR | |
| SCHEMBL27369469 | 0.78 | MAPT (0.51) | TDP1MAPTMAPK1RORCTSHR | |
| SCHEMBL27455401 | 0.77 | TSHR (0.68) | TDP1MAPTMAPK1TSHRPOLB | |
| SCHEMBL6905688 | 0.77 | GPR35 (0.56) | TDP1MAPTMAPK1TSHRPOLB | |
| SCHEMBL10441240 | 0.76 | ALOX15 (0.50) | TDP1MAPTMAPK1RORCTSHR | |
| SCHEMBL16581418 | 0.76 | TSHR (0.55) | RORCTSHRCYP3A4HPGDHDAC4 | |
| SCHEMBL8041378 | 0.75 | SMN1; SMN2 (0.51) | TDP1MAPTMAPK1RORCTSHR | |
| SCHEMBL16225013 | 0.74 | TDP1 (0.50) | TDP1MAPTMAPK1TSHRGPR35 | |
| SCHEMBL11686194 | 0.74 | GPR35 (0.50) | TDP1MAPTMAPK1TSHRGPR35 | |
| SCHEMBL6680488 | 0.73 | ALDH1A1 (0.50) | TDP1MAPTMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105440252-A | UV-curable waterborne polyurethane modified epoxy itaconic acid resin and preparation method thereof | UNIV GUANGZHOU | 2016-03-30 | — | — | CN | claimed |
| CN-105440252-A | UV-curable waterborne polyurethane modified epoxy itaconic acid resin and preparation method thereof | UNIV GUANGZHOU | 2016-03-30 | — | — | CN | disclosed |