SCHEMBL2806326

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2805019	0.90	GABRD (0.43)	CYP2C19KDM4ECYP1A2CYP3A4LMNA
	SCHEMBL2802920	0.90	KDM4E (0.46)	CYP2C19KDM4ECYP1A2CYP3A4CYP2C9
	SCHEMBL2802255	0.90	CYP1A2 (0.43)	CYP2C19CYP1A2CYP3A4LMNAHTR1A
	SCHEMBL2808004	0.90	HTR1A (0.47)	HPGDHTR1ALRRK2
	SCHEMBL2802572	0.90	MAPK1 (0.48)	CYP2C19CYP1A2CYP3A4CYP2C9HPGD
	SCHEMBL17057525	0.90	PDK2 (0.38)	CYP2C19KDM4ECYP1A2CYP3A4CYP2C9
	SCHEMBL2806025	0.89	HTR1A (0.50)	HTR1A
	SCHEMBL2802776	0.89	LMNA (0.47)	KDM4ELMNAHPGDPKMALDH1A1
	SCHEMBL2802240	0.88	HTR1A (0.47)	LMNAPOLBMAPTHPGDHTT
	SCHEMBL2802615	0.87	CCNT1 (0.41)	CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.