Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064078 | 0.94 | TEAD1 (0.45) | KDM4EALDH1A1LMNATEAD1TEAD3 | |
| SCHEMBL28064128 | 0.83 | TEAD1 (0.40) | KDM4EALDH1A1TEAD1TEAD3GAA | |
| SCHEMBL28827928 | 0.83 | MEN1 (0.39) | TEAD1TEAD3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28064062 | 0.82 | RAB9A (0.39) | ALDH1A1LMNATEAD1TEAD3PPARG | |
| SCHEMBL28064064 | 0.82 | TEAD1 (0.41) | KDM4EALDH1A1TEAD1TEAD3GAA | |
| SCHEMBL2228538 | 0.82 | TEAD1 (0.45) | KDM4EALDH1A1LMNATEAD1TEAD3 | |
| SCHEMBL28064072 | 0.81 | ALDH1A1 (0.39) | KDM4EALDH1A1TEAD1TEAD3MEN1 | |
| SCHEMBL28064077 | 0.80 | KDM4E (0.44) | KDM4EALDH1A1TEAD1TEAD3GAA | |
| SCHEMBL28064080 | 0.80 | HRH3 (0.39) | LMNATEAD1TEAD3GAASMN1; SMN2 | |
| SCHEMBL28064071 | 0.79 | ALDH1A1 (0.38) | KDM4EALDH1A1LMNAGAAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |