Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL193828 | 0.89 | TSHR (0.50) | ALDH1A1TSHRFGFR4 | |
| Acrylamide SCHEMBL29102421 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TSHRFGFR4 | |
| Nitric Acid SCHEMBL27715877 | 0.82 | CA5A (0.42) | ALDH1A1TSHRPOLBHTTHCAR3 | |
| Acrylamide SCHEMBL2588866 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRFGFR4 | |
| Nitric Acid SCHEMBL27980254 | 0.81 | ALDH1A1 (0.34) | ALDH1A1TSHRPOLBHTT | |
| Acrylamide SCHEMBL28263729 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4 | |
| Acrylamide SCHEMBL29055669 | 0.78 | — | — | |
| Acrylamide SCHEMBL27560789 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRFGFR4 | |
| Acrylamide SCHEMBL11759283 | 0.77 | TSHR (0.50) | ALDH1A1TSHRFGFR4 | |
| Octadecanoic Acid Amide SCHEMBL28755266 | 0.76 | FAAH (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958620-B | The antistatic coating composition of using | KAO CORP. (JP) | 2016-05-04 | — | — | CN | disclosed |