SCHEMBL28064180

SCHEMBL28064180

O=S(=O)(O)S(=O)(=O)OCc1cc(F)cc(F)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.45
MMP2 P08253 2/20 0.37
MMP9 P14780 2/20 0.37
MMP14 P50281 1/20 0.37
ADAM17 P78536 1/20 0.37
BACE1 P56817 3/20 0.36
GSK3B P49841 2/20 0.36
MMP1 P03956 1/20 0.36
MMP12 P39900 1/20 0.36
CA9 Q16790 2/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
MAOB P27338 1/20 0.31
ACHE P22303 1/20 0.31
F13A1 P00488 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28064274 0.77 MAOB (0.44) CA9CA1CA2CES2CES1
SCHEMBL20868558 0.76 IDO1 (0.48) IDO1MMP2MMP9MMP14ADAM17
SCHEMBL21407665 0.73 CA2 (0.53) IDO1MMP2MMP9MMP14ADAM17
SCHEMBL27702475 0.72 CA2 (0.59) IDO1MMP2MMP9MMP1CA9
SCHEMBL28064177 0.72 PSEN1 (0.43) IDO1MMP2MMP9MMP1MMP12
SCHEMBL776942 0.69 IDO1 (0.38) IDO1MMP2MMP9MMP14ADAM17
SCHEMBL21407644 0.67 CA1 (0.45) IDO1MMP2MMP9MMP14ADAM17
SCHEMBL1791163 0.67 IDO1 (0.52) IDO1MMP2MMP9MMP14ADAM17
SCHEMBL3942239 0.66 IDO1 (0.37) IDO1MMP2MMP9MMP14ADAM17
SCHEMBL778663 0.65 DAO (0.38) IDO1MMP2MMP9MMP14ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103748730-B Nonaqueous electrolyte solution and electricity storage device using same 宇部兴产株式会社 2016-06-08 CN disclosed