Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942239 | 0.87 | IDO1 (0.37) | IDO1MMP9MMP2MMP14ADAM17 | |
| SCHEMBL16399039 | 0.84 | IDO1 (0.43) | IDO1ALDH1A1KMT2A | |
| SCHEMBL14109586 | 0.82 | HCRTR2 (0.40) | IDO1 | |
| SCHEMBL778647 | 0.81 | IDO1 (0.55) | IDO1MAOB | |
| SCHEMBL31385471 | 0.81 | CA12 (0.42) | KDM4EALDH1A1LMNACA9CA2 | |
| SCHEMBL4966993 | 0.81 | CA12 (0.42) | KDM4EALDH1A1LMNACA9CA2 | |
| SCHEMBL10204294 | 0.80 | CYP1A2 (0.34) | MMP9KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL22817377 | 0.80 | CA2 (0.35) | MMP9KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL5033774 | 0.80 | KDM4E (0.41) | IDO1MMP9KDM4EUSP2ALDH1A1 | |
| SCHEMBL2113033 | 0.80 | TLR7 (0.42) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112055712-A | Processes and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2020-12-08 | — | — | CN | claimed |
| CN-116854630-B | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2026-05-19 | — | — | CN | disclosed |
| US-20260078123-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | SHANGHAI DAIDAI INVESTMENT CONSULTING CO., LTD (CN) | 2026-03-19 | — | — | US | disclosed |
| US-12516054-B2 | Pyrazolo[1,5-a]pyridine derivatives, preparation method therefor and use thereof | SHANGHAI DAIDAI INVESTMENT CONSULTING CO., LTD (CN) | 2026-01-06 | — | — | US | disclosed |
| US-20250100999-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2025-03-27 | — | — | US | disclosed |
| CN-118978537-A | Pyrazolo [1,5-a ] pyridine derivative, preparation method and application thereof | 上海岱岱投资咨询有限公司 | 2024-11-19 | — | — | CN | disclosed |
| US-12122765-B2 | Methods and intermediates for preparing therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2024-10-22 | — | — | US | disclosed |
| CN-113508116-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method and application thereof | 察略盛医药科技(上海)有限公司 | 2024-08-13 | — | — | CN | disclosed |
| US-20240101533-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2024-03-28 | — | — | US | disclosed |
| CN-116854630-A | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-111212830-B | N- (substituted sulfonyl) benzamide derivative and preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| US-20220135560-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | CLUES THERAPEUTICS (SHANGHAI) LTD (CN) | 2022-05-05 | — | — | US | disclosed |
| US-20220009904-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2022-01-13 | — | — | US | disclosed |
| US-11117886-B2 | Methods and intermediates for preparing therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2021-09-14 | — | — | US | disclosed |
| CN-112055712-A | Processes and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2020-12-08 | — | — | CN | disclosed |
| US-20200369647-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2020-11-26 | — | — | US | disclosed |
| US-10696657-B2 | Methods and intermediates for preparing therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190300505-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2019-10-03 | — | — | US | disclosed |
| CN-109574927-A | N- (substituted sulphonyl) benzamide derivatives and preparation method thereof and medical usage | 浙江海正药业股份有限公司 | 2019-04-05 | — | — | CN | disclosed |
| WO-2019062848-A1 | N-(SUBSTITUTED SULFONYL)BENZAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190300505-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | CYP11A1, CYP11B1, CYP11B2 | IDO1 3259/4885MMP9 2941/4885MMP2 2024/4885 |
| US-12122765-B2 | Methods and intermediates for preparing therapeutic compounds | CYP11A1, CYP11B1, CYP11B2 | IDO1 3259/4885MMP9 2941/4885MMP2 2024/4885 |
| US-20220009904-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | CYP11A1, CYP11B1, CYP11B2 | IDO1 3240/4885MMP9 2949/4885MMP2 1998/4885 |
| US-20260078123-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | NR3C1, CXCR1, CCR1 | IDO1 4380/4885MMP9 4094/4885MMP2 3476/4885 |
| US-11117886-B2 | Methods and intermediates for preparing therapeutic compounds | CYP11A1, CYP11B1, CYP11B2 | IDO1 3259/4885MMP9 2941/4885MMP2 2024/4885 |
| US-10696657-B2 | Methods and intermediates for preparing therapeutic compounds | CYP11A1, CYP11B1, CYP11B2 | IDO1 3259/4885MMP9 2941/4885MMP2 2024/4885 |
| US-20240101533-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | CYP11A1, CYP11B1, CYP11B2 | IDO1 3259/4885MMP9 2941/4885MMP2 2024/4885 |
| US-20250100999-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | CYP11A1, CYP11B1, CYP11B2 | IDO1 3259/4885MMP9 2941/4885MMP2 2024/4885 |
| US-20200369647-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | CYP11A1, CYP11B1, CYP11B2 | IDO1 3259/4885MMP9 2941/4885MMP2 2024/4885 |
| US-20220135560-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | RET, RIN1, WEE1 | IDO1 4042/4885MMP9 4302/4885MMP2 4266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.