SCHEMBL28064274

SCHEMBL28064274

O=S(=O)(O)S(=O)(=O)OCc1ccc(F)c(F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.44
MAOA P21397 2/20 0.44
CA2 P00918 2/20 0.37
CA9 Q16790 1/20 0.37
ACHE P22303 1/20 0.35
PPARA Q07869 1/20 0.35
KDM5A P29375 2/20 0.34
KDM5B Q9UGL1 2/20 0.34
GRM2 Q14416 1/20 0.34
GRM3 Q14832 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
HTT P42858 2/20 0.34
ALDH1A1 P00352 1/20 0.34
RIPK1 Q13546 1/20 0.34
CA1 P00915 1/20 0.33
KMT2A Q03164 1/20 0.33
DAO P14920 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
BMP1 P13497 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28064180 0.77 IDO1 (0.45) MAOBCA2CA9ACHECA1
SCHEMBL28064177 0.75 PSEN1 (0.43) MAOBCA9RIPK1CES2CES1
SCHEMBL27702475 0.72 CA2 (0.59) CA2CA9ALDH1A1CA1KMT2A
SCHEMBL28827937 0.71 MMP1 (0.40) CA2CA9ALDH1A1CA1KMT2A
SCHEMBL7889545 0.71 MAOB (0.47) MAOBMAOAACHEPPARAGRM2
Hydrochloric Acid SCHEMBL28163857 0.71 MAOB (0.38) MAOBMAOAKDM5AKDM5BHTT
SCHEMBL4808098 0.69 MAOB (0.46) MAOBMAOAACHEPPARAGRM2
SCHEMBL28578149 0.68 MAOA (0.50) MAOBMAOAPPARAKDM5AKDM5B
SCHEMBL13034150 0.68 MAOB (0.58) MAOBMAOACA2ACHEHTT
SCHEMBL28064189 0.68 AKR1B1 (0.38) MAOBALDH1A1RIPK1KMT2ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103748730-B Nonaqueous electrolyte solution and electricity storage device using same 宇部兴产株式会社 2016-06-08 CN disclosed