Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.57 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830625 | 0.87 | TEAD1 (0.73) | TEAD1TEAD3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5208507 | 0.86 | TEAD1 (0.57) | TEAD1TEAD3MEN1POLBKMT2A | |
| SCHEMBL13519209 | 0.86 | MEN1 (0.56) | MEN1POLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28802165 | 0.84 | TEAD1 (0.55) | TEAD1TEAD3SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL4159824 | 0.83 | GPR119 (0.65) | GPR119 | |
| SCHEMBL3356937 | 0.83 | TEAD1 (0.60) | TEAD1TEAD3KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5212355 | 0.83 | TEAD1 (0.54) | TEAD1TEAD3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5231915 | 0.82 | GRIN2B (0.57) | TEAD1TEAD3MEN1POLBKMT2A | |
| SCHEMBL4744702 | 0.82 | TEAD1 (0.43) | TEAD1TEAD3MEN1POLBKMT2A | |
| SCHEMBL20744741 | 0.82 | TEAD1 (0.53) | TEAD1TEAD3MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-102803258-A | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SANOFI AVENTIS | 2012-11-28 | — | — | CN | claimed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |