Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.54 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ATF4 | P18848 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830625 | 0.84 | TEAD1 (0.73) | TEAD1TEAD3KMT2AMEN1HPGD | |
| SCHEMBL28064208 | 0.83 | TEAD1 (0.57) | TEAD1TEAD3KMT2AMEN1ALDH1A1 | |
| SCHEMBL5208507 | 0.83 | TEAD1 (0.57) | TEAD1TEAD3KMT2AMEN1ALDH1A1 | |
| SCHEMBL28802165 | 0.81 | TEAD1 (0.55) | TEAD1TEAD3HPGDALDH1A1CHEK2 | |
| SCHEMBL2463633 | 0.80 | FAAH (0.69) | TEAD1TEAD3KMT2AMEN1HPGD | |
| SCHEMBL4322579 | 0.80 | GPR119 (0.65) | KMT2AMEN1HPGDALDH1A1LMNA | |
| SCHEMBL3356937 | 0.80 | TEAD1 (0.60) | TEAD1TEAD3KMT2AALDH1A1LMNA | |
| SCHEMBL20744741 | 0.79 | TEAD1 (0.53) | TEAD1TEAD3KMT2AMEN1 | |
| SCHEMBL23453708 | 0.78 | NFE2L2 (0.53) | TEAD1TEAD3HPGD | |
| SCHEMBL2792293 | 0.77 | TEAD1 (0.47) | TEAD1TEAD3KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708994-B1 | ARYLOXYALKYLCARBAMATE-TYPE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-08-08 | — | — | EP | claimed |
| EP-1708994-B1 | ARYLOXYALKYLCARBAMATE-TYPE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-08-08 | — | — | EP | disclosed |