Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 16/20 | 0.65 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28827931 | 0.81 | LIPE (0.47) | LIPE | |
| SCHEMBL28064270 | 0.79 | LIPE (0.64) | LIPEALDH1A1 | |
| SCHEMBL13835642 | 0.79 | LIPE (1.00) | LIPE | |
| SCHEMBL13835422 | 0.79 | LIPE (1.00) | LIPE | |
| SCHEMBL28064277 | 0.77 | LIPE (0.67) | LIPE | |
| SCHEMBL28064359 | 0.77 | LIPE (0.69) | LIPE | |
| SCHEMBL28064278 | 0.76 | LIPE (0.65) | LIPEACACB | |
| SCHEMBL28064215 | 0.76 | LIPE (0.42) | LIPE | |
| SCHEMBL28064214 | 0.74 | LIPE (0.68) | LIPEALDH1A1 | |
| SCHEMBL28064269 | 0.72 | LIPE (0.69) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103562180-B | Novel six hydrogen cyclopenta pyrrolidone, hexahydropyrrolo pyrrolidone, octahydro pyrrolopyridinone and octahydro pyridinone compounds | HOFFMAN-LA ROCHE LTD. (CH) | 2016-04-20 | — | — | CN | disclosed |