Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 15/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27951609 | 0.85 | LIPE (0.38) | LIPEHTR2CHTR2AHTR2BHRH3 | |
| SCHEMBL28827931 | 0.77 | LIPE (0.47) | LIPE | |
| SCHEMBL28064270 | 0.76 | LIPE (0.64) | LIPE | |
| SCHEMBL28064213 | 0.76 | LIPE (0.65) | LIPE | |
| SCHEMBL28064278 | 0.76 | LIPE (0.65) | LIPE | |
| SCHEMBL28064214 | 0.76 | LIPE (0.68) | LIPE | |
| SCHEMBL28064277 | 0.74 | LIPE (0.67) | LIPE | |
| SCHEMBL13966325 | 0.74 | LIPE (0.59) | LIPE | |
| SCHEMBL13835282 | 0.74 | LIPE (0.59) | LIPE | |
| SCHEMBL28064359 | 0.72 | LIPE (0.69) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103562180-B | Novel six hydrogen cyclopenta pyrrolidone, hexahydropyrrolo pyrrolidone, octahydro pyrrolopyridinone and octahydro pyridinone compounds | HOFFMAN-LA ROCHE LTD. (CH) | 2016-04-20 | — | — | CN | disclosed |