Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 10/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064278 | 0.87 | LIPE (0.65) | LIPE | |
| SCHEMBL13835983 | 0.81 | LIPE (1.00) | LIPE | |
| SCHEMBL13835728 | 0.81 | LIPE (1.00) | LIPE | |
| SCHEMBL28827931 | 0.76 | LIPE (0.47) | LIPE | |
| SCHEMBL28064215 | 0.76 | LIPE (0.42) | LIPE | |
| SCHEMBL28064213 | 0.74 | LIPE (0.65) | LIPEALDH1A1 | |
| SCHEMBL28064270 | 0.73 | LIPE (0.64) | LIPEALDH1A1MEN1KMT2A | |
| SCHEMBL13836332 | 0.73 | LIPE (1.00) | LIPE | |
| SCHEMBL13836201 | 0.73 | LIPE (1.00) | LIPE | |
| SCHEMBL13835673 | 0.71 | LIPE (1.00) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103562180-B | Novel six hydrogen cyclopenta pyrrolidone, hexahydropyrrolo pyrrolidone, octahydro pyrrolopyridinone and octahydro pyridinone compounds | HOFFMAN-LA ROCHE LTD. (CH) | 2016-04-20 | — | — | CN | disclosed |