SCHEMBL28064220

SCHEMBL28064220

O=C(CS(=O)(=O)Nc1ccc(Cl)cc1C(F)(F)F)C1(Cl)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HTT P42858 1/20 0.41
PAX8 Q06710 1/20 0.41
TP53 P04637 3/20 0.40
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TRPV1 Q8NER1 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LMNA P02545 1/20 0.39
SLC22A12 Q96S37 1/20 0.38
POLB P06746 2/20 0.38
CNR2 P34972 1/20 0.38
GAA P10253 1/20 0.38
CRHBP P24387 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28639449 0.79 RAB9A (0.48) RAB9ACYP1A2CYP2D6CYP2C19KDM4E
SCHEMBL28069398 0.77 RAB9A (0.49) RAB9ACYP1A2CYP2D6CYP2C19KDM4E
SCHEMBL28311648 0.76 RAB9A (0.48) RAB9ACYP1A2CYP2D6CYP2C19KDM4E
SCHEMBL9323154 0.68 KMT2A (0.49) ALDH1A1HTTMAPTLMNAGAA
SCHEMBL12609252 0.67 RAB9A (0.62) RAB9ACYP1A2CYP2D6CYP2C19KDM4E
SCHEMBL10885626 0.66 RAB9A (0.69) RAB9ACYP1A2CYP2D6CYP2C19KDM4E
SCHEMBL1122648 0.66 KMT2A (0.49) RAB9ANPC1ALDH1A1MAPTSMN1; SMN2
SCHEMBL3929131 0.65 RAB9A (0.56) RAB9ACYP1A2CYP2D6CYP2C19KDM4E
SCHEMBL9499786 0.65 KMT2A (0.46) MAPTSMN1; SMN2KMT2ACCR2MRGPRX1
SCHEMBL11415125 0.65 RAB9A (0.58) RAB9ACYP1A2CYP2D6CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105669541-B 2- amide groups naphthene sulfamide amine compounds and preparation method and as sterilization, herbicide purposes 沈阳农业大学 2019-02-26 CN disclosed
CN-105669541-A 2-amido cycloalkylsulfonamide compound, preparation method and application thereof as bactericide and herbicide 沈阳农业大学 2016-06-15 CN disclosed