Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | IDH2 | P48735 | 2/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363632 | 0.87 | KMT2A (0.49) | KMT2AIDH2MRGPRX1ARMEN1 | |
| SCHEMBL9363911 | 0.86 | IDH2 (0.41) | KMT2AIDH2MRGPRX1MRGPRX4PTGES2 | |
| SCHEMBL9367106 | 0.85 | KMT2A (0.47) | KMT2AIDH2MRGPRX1ARMEN1 | |
| SCHEMBL9499786 | 0.85 | KMT2A (0.46) | KMT2AIDH2MRGPRX1ARACLY | |
| SCHEMBL9321851 | 0.83 | KMT2A (0.55) | KMT2AACLYALDH1A1LMNAGAA | |
| SCHEMBL9363735 | 0.83 | KMT2A (0.46) | KMT2AIDH2MRGPRX1 | |
| SCHEMBL9363767 | 0.82 | KMT2A (0.47) | KMT2AIDH2MRGPRX1MRGPRX4AR | |
| SCHEMBL9363652 | 0.81 | KMT2A (0.46) | KMT2AIDH2MRGPRX1ARALDH1A1 | |
| SCHEMBL9367195 | 0.80 | KMT2A (0.47) | KMT2AIDH2MRGPRX1MRGPRX4AR | |
| SCHEMBL9368626 | 0.80 | IDH2 (0.40) | KMT2AIDH2MRGPRX1PTGES2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447013-B1 | Fluorobenzene sulphonamides | SCHERING AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| EP-0368429-B1 | Fluor-substituted benzene derivatives | SCHERING AG (DE) | 1994-02-09 | — | — | EP | disclosed |
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |
| US-5130119-A | Sulfonamide or hydroxy fluorine substituted benzene for medical diagnosis | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0447013-A1 | Fluorobenzene sulphonamides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |
| EP-0368429-A2 | Fluor-substituted benzene derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-05-16 | — | — | EP | disclosed |