Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.53 |
| ▸ | LAP3 | P28838 | 5/20 | 0.46 |
| ▸ | ANPEP | P15144 | 4/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL7195845 | 0.87 | CA12 (0.42) | SNCALAP3ANPEPACP3CYP1A2 | |
| SCHEMBL29918368 | 0.87 | SNCA (0.65) | SNCALAP3ANPEPHIF1ACYP1A2 | |
| SCHEMBL7874618 | 0.85 | SNCA (0.59) | SNCAHIF1ACYP1A2TSHRALDH1A1 | |
| Water SCHEMBL3422802 | 0.84 | SNCA (0.63) | SNCALAP3ANPEPHIF1ACYP1A2 | |
| SCHEMBL989761 | 0.84 | SNCA (0.63) | SNCALAP3ANPEPHIF1ACYP1A2 | |
| Iodide SCHEMBL159922 | 0.84 | SNCA (0.63) | SNCALAP3ANPEPHIF1ACYP1A2 | |
| Fluoride Ion SCHEMBL585089 | 0.84 | SNCA (0.63) | SNCALAP3ANPEPHIF1ACYP1A2 | |
| Bromide SCHEMBL163158 | 0.84 | SNCA (0.67) | SNCALAP3ANPEPHIF1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL494 | 0.84 | SNCA (0.63) | SNCALAP3ANPEPHIF1ACYP1A2 | |
| SCHEMBL6890093 | 0.83 | SNCA (0.53) | SNCALAP3ANPEPHIF1AACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106633544-B | A kind of high temperature high voltage resistant sealing element fluorubber material and preparation method thereof | 上海如实密封科技有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-105860179-B | Rubber seal productses and its preparation method and application | 上海如实密封科技有限公司 | 2017-12-12 | — | — | CN | disclosed |
| CN-106633544-A | A fluororubber material used for sealing members resistant to high temperatures and high pressure and a preparing method thereof | 上海如实密封科技有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-105860179-A | Rubber sealing product and preparation method and application thereof | 上海如实密封科技有限公司 | 2016-08-17 | — | — | CN | disclosed |