Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21499324 | 0.80 | DHODH (0.73) | CSF1RMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28780838 | 0.75 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL21499309 | 0.73 | DHODH (0.57) | CSF1RMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1599730 | 0.71 | MEN1 (0.63) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL21468524 | 0.70 | DHODH (0.70) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL6101614 | 0.69 | SMN1; SMN2 (0.53) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL11674790 | 0.68 | RORC (0.52) | ALDH1A1MAPTRORCNPC1RAB9A | |
| SCHEMBL11564250 | 0.68 | RORC (0.52) | ALDH1A1MAPTRORCNPC1RAB9A | |
| SCHEMBL6102025 | 0.68 | SMN1; SMN2 (0.54) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL11487284 | 0.68 | MEN1 (0.51) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566265-A | Antagonists of the glucagon receptor | METABASIS THERAPEUTICS INC | 2016-05-11 | — | — | CN | disclosed |