Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 7/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355804 | 0.78 | HDAC8 (0.46) | EGLN2ALDH1A1CYP2A6KIF11CYP11B2 | |
| SCHEMBL28310880 | 0.75 | PCSK9 (0.52) | EGLN2PCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL6444709 | 0.74 | PCSK9 (0.73) | PCSK9ALDH1A1CYP2A6CYP2A13SLC6A3 | |
| SCHEMBL11359663 | 0.74 | PCSK9 (0.50) | EGLN2PCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL3188837 | 0.74 | PCSK9 (0.50) | PCSK9ALDH1A1CYP2A6CYP2A13SLC6A3 | |
| SCHEMBL11357896 | 0.74 | PCSK9 (0.50) | EGLN2PCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL1026027 | 0.74 | PCSK9 (0.50) | PCSK9ALDH1A1CYP2A6CYP2A13OTUD7B | |
| SCHEMBL197196 | 0.71 | PCSK9 (0.60) | PCSK9ALDH1A1CYP2A6CYP2A13TSHR | |
| SCHEMBL11356121 | 0.71 | PCSK9 (0.47) | EGLN2PCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL26529342 | 0.71 | PCSK9 (0.47) | PCSK9ALDH1A1CYP2A6CYP2A13KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105568312-A | Method for synthesizing 2-arylpyrrole-compound through indirect electro-catalysis | UNIV SUN YAT SEN | 2016-05-11 | — | — | CN | disclosed |