Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 7/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064456 | 0.78 | EGLN2 (0.46) | EGLN2CYP2A6CYP11B2TSHRKIF11 | |
| SCHEMBL30729513 | 0.74 | KIF11 (0.47) | KIF11ALDH1A1KDM4E | |
| SCHEMBL8206801 | 0.70 | HSD17B2 (0.44) | — | |
| SCHEMBL16406843 | 0.68 | ADRA1A (0.33) | ALDH1A1KDM4EMAPK1 | |
| SCHEMBL31729550 | 0.67 | PCSK9 (0.46) | CYP2A6TSHRHSD17B10ALDH1A1KDM4E | |
| Water SCHEMBL11055485 | 0.66 | MMP3 (0.74) | CYP2A6CYP11B2TSHRHSD17B10KIF11 | |
| SCHEMBL396846 | 0.66 | MMP3 (0.74) | CYP2A6CYP11B2TSHRHSD17B10KIF11 | |
| SCHEMBL26246 | 0.66 | MMP3 (0.74) | CYP2A6CYP11B2TSHRHSD17B10KIF11 | |
| SCHEMBL13063633 | 0.66 | MMP3 (0.74) | CYP2A6CYP11B2TSHRHSD17B10KIF11 | |
| Ethylamine SCHEMBL8419053 | 0.66 | TSHR (0.52) | CYP2A6CYP11B2TSHRHSD17B10KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243795-A | Polyphosphazene copolymers containing N-substituted pyrrole substituents | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-01-06 | — | — | US | disclosed |