Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 7/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 2/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | TGM1 | P22735 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27955423 | 0.84 | ALDH1A1 (0.56) | TSHRALDH1A1GAACTSLCTSB | |
| Tert-Butyl Formate SCHEMBL28112836 | 0.80 | ALDH1A1 (0.51) | TSHRALDH1A1GAACTSLCTSB | |
| Tert-Butyl Formate SCHEMBL28112834 | 0.80 | ALDH1A1 (0.51) | TSHRALDH1A1GAACTSLCTSB | |
| Tert-Butyl Formate SCHEMBL28875608 | 0.79 | EPHX1 (0.50) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL7870 | 0.79 | L3MBTL1 (0.58) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL13402357 | 0.79 | ALDH1A1 (0.67) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL3944460 | 0.78 | ALDH1A1 (0.69) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL6153463 | 0.78 | ALDH1A1 (0.69) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL3944464 | 0.78 | ALDH1A1 (0.69) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL21228046 | 0.77 | ALDH1A1 (0.58) | TSHRALDH1A1GAACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028491-A | Fibroblast growth factor receptor inhibitor | 蓝图药品公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-105658642-B | Fibroblast growth factor receptor inhibitors | 蓝图药品公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-105658642-A | Fibroblast growth factor receptor inhibitors | 蓝图药品公司 | 2016-06-08 | — | — | CN | disclosed |