SCHEMBL28064761

SCHEMBL28064761

COC(=O)OB(O)Oc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 5/20 0.44
MTNR1B P49286 5/20 0.44
KMT2A Q03164 2/20 0.40
HPGD P15428 3/20 0.40
KDM4E B2RXH2 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TSHR P16473 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
RAB9A P51151 1/20 0.38
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
GAA P10253 1/20 0.37
CA4 P22748 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28120446 0.81 ELANE (0.40) MTNR1AMTNR1BHPGDKDM4EHSD17B10
SCHEMBL6931923 0.81 NPC1 (0.42) KMT2AHPGDTSHRSMN1; SMN2TDP1
SCHEMBL9561745 0.80 ALOX15 (0.39) MTNR1AMTNR1BHPGDHSD17B10TSHR
SCHEMBL28094507 0.80 ALDH1A1 (0.40) MTNR1AMTNR1BKMT2AHPGDKDM4E
SCHEMBL28164017 0.80 HTT (0.43) MTNR1AMTNR1BKMT2AHPGDKDM4E
SCHEMBL27447997 0.77 PARP10 (0.41) KMT2AHSD17B10TSHRSMN1; SMN2TDP1
SCHEMBL28226322 0.76 PKM (0.44) KMT2ATSHRSMN1; SMN2TDP1ALDH1A1
SCHEMBL29250 0.76 HPGD (0.57) MTNR1AMTNR1BKMT2AHPGDKDM4E
SCHEMBL27496383 0.76 HPGD (0.57) MTNR1AMTNR1BKMT2AHPGDKDM4E
SCHEMBL3900141 0.76 CA4 (0.46) HPGDTSHRSMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104844400-B Preparation method for 9-fluorenone and T type oligomeric phenylene skeleton compounds 南京邮电大学 2017-03-22 CN claimed
CN-119143760-B Organic compound and application thereof 西安瑞联新材料股份有限公司 2025-02-28 CN disclosed
CN-105873916-B Amide derivatives for GPR119 agonists 株式会社钟根堂 2019-08-27 CN disclosed
CN-110028494-A Amide derivatives, its stereoisomer or its pharmaceutically acceptable salt and the pharmaceutical composition comprising it 株式会社钟根堂 2019-07-19 CN disclosed
CN-108440515-A Substituted benzofuranyl and benzoxazole based compound and application thereof 卡尔约药物治疗公司 2018-08-24 CN disclosed
CN-104364246-B Piperidine derivatives useful as GPR119 agonists 株式会社钟根堂 2018-05-22 CN disclosed
CN-105492437-B Substituted benzofuranyl and benzoxazolyl compounds and uses thereof 卡尔约药物治疗公司 2018-05-11 CN disclosed
CN-105037061-B A kind of utilize borinic acid, amine and the method for carbon dioxide synthesis of carbamates 华南理工大学 2016-10-05 CN disclosed
CN-105873916-A Amide derivatives for GPR119 agonists 株式会社钟根堂 2016-08-17 CN disclosed
CN-102985438-B As the C-28 acid amides of the modified C-3 betulinic acid derivative of the ripe inhibitor of HIV BRISTOL-MYERS SQUIBB CO. (US) 2016-05-18 CN disclosed