SCHEMBL28064783

SCHEMBL28064783

CC(C)(C)c1c(O)ccc(CCCCl)c1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.34
MAPT P10636 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
ALOX15 P16050 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX5 P09917 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP2D6 P10635 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9074096 0.84 TYR (0.50) TYRMAPTALDH1A1RAB9ANPSR1
SCHEMBL2097901 0.82 TYR (0.30) TYR
SCHEMBL28035798 0.82 TYR (0.34) TYRMAPTALDH1A1ALOX15TDP1
SCHEMBL816624 0.81 TYR (0.56) TYRMAPTALDH1A1ALOX15TDP1
SCHEMBL11495521 0.81 TYR (0.56) TYRMAPTALDH1A1ALOX15TDP1
SCHEMBL27880027 0.81 TYR (0.56) TYRMAPTALDH1A1ALOX15TDP1
SCHEMBL11577351 0.78 IGF1R (0.45) CASP3RAB9ASENP8SENP7SENP6
SCHEMBL6561982 0.77 ALDH1A1 (0.37) TYRMAPTALDH1A1ALOX15TDP1
SCHEMBL29399700 0.77 ALDH1A1 (0.37) TYRMAPTALDH1A1ALOX15TDP1
SCHEMBL932105 0.75 KLF10 (0.47) TYRMAPTALDH1A1RAB9AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105505525-B Phenol amine antioxidants, preparation method and application 中国科学院宁波材料技术与工程研究所 2018-09-11 CN claimed
CN-105505525-A Phenolic amine antioxidant and preparation method and application thereof NINGBO INST MAT TECH & ENG CAS 2016-04-20 CN claimed
CN-105505525-A Phenolic amine antioxidant and preparation method and application thereof NINGBO INST MAT TECH & ENG CAS 2016-04-20 CN disclosed