SCHEMBL28035798

SCHEMBL28035798

CC(C)(C)c1c(O)ccc(CCCS)c1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.34
ALOX15 P16050 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX5 P09917 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP2D6 P10635 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KLF10 Q13118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9074096 0.84 TYR (0.50) TYRALOX15TDP1MEN1TP53
SCHEMBL28064783 0.82 TYR (0.34) TYRALOX15TDP1MEN1TP53
SCHEMBL27880027 0.81 TYR (0.56) TYRALOX15TDP1MEN1TP53
SCHEMBL11495521 0.81 TYR (0.56) TYRALOX15TDP1MEN1TP53
SCHEMBL816624 0.81 TYR (0.56) TYRALOX15TDP1MEN1TP53
SCHEMBL11577351 0.78 IGF1R (0.45) ALOX15TDP1
SCHEMBL6561982 0.77 ALDH1A1 (0.37) TYRALOX15TDP1MEN1TP53
SCHEMBL29399700 0.77 ALDH1A1 (0.37) TYRALOX15TDP1MEN1TP53
SCHEMBL932105 0.75 KLF10 (0.47) TYRALOX15TDP1MEN1MAPT
SCHEMBL2040206 0.75 GABRA1 (0.43) TYRALOX15TDP1HTTCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105566720-A Polymer composition and application thereof CHINA PETROLEUM & CHEM CORP 2016-05-11 CN disclosed
CN-105315183-A Screen phenol compound and its manufacturing method and use as anti-oxidant CHINA PETROLEUM & CHEMICAL 2016-02-10 CN disclosed
CN-105272892-A Hindered phenol compound, preparation method thereof, and application thereof as antioxidant CHINA PETROLEUM & CHEMICAL 2016-01-27 CN disclosed
CN-105218420-A A kind ofly shield phenolic compound, its manufacture method and the application as oxidation inhibitor thereof CHINA PETROLEUM & CHEMICAL 2016-01-06 CN disclosed
CN-105130859-A Screen phenol compound, manufacturing method and application thereof as antioxidant CHINA PETROLEUM & CHEMICAL 2015-12-09 CN disclosed