Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804069 | 0.81 | MAPT (0.47) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL28237020 | 0.76 | NPSR1 (0.44) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL8949893 | 0.75 | CA9 (0.40) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL4425506 | 0.72 | GAA (0.55) | MAPTALDH1A1CA12CA9SMN1; SMN2 | |
| SCHEMBL29200269 | 0.71 | ALDH1A1 (0.52) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL4424542 | 0.69 | CA1 (0.53) | ALDH1A1CA2KMT2A | |
| SCHEMBL29286615 | 0.68 | NPSR1 (0.40) | MAPTCA12CA9NPSR1SMN1; SMN2 | |
| SCHEMBL3360810 | 0.68 | TSHR (0.39) | ALDH1A1CA12CA9SMN1; SMN2TP53 | |
| SCHEMBL698616 | 0.68 | TSHR (0.48) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL27779751 | 0.68 | CA2 (0.46) | MAPTALDH1A1CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646579-B | [base of 2 (1H) quinolinone 3] phenylaminomethyl phosphonate ester as cancer therapy drug application | 湖南大学 | 2017-10-24 | — | — | CN | claimed |
| CN-105646579-A | Application of [2-(1H)-quinolinone-3-yl]phenylamino methylphosphonate as anti-cancer drug | 湖南大学 | 2016-06-08 | — | — | CN | claimed |
| CN-105646579-B | [base of 2 (1H) quinolinone 3] phenylaminomethyl phosphonate ester as cancer therapy drug application | 湖南大学 | 2017-10-24 | — | — | CN | disclosed |
| CN-105646579-B | [base of 2 (1H) quinolinone 3] phenylaminomethyl phosphonate ester as cancer therapy drug application | 湖南大学 | 2017-10-24 | — | — | CN | disclosed |
| CN-105646579-B | [base of 2 (1H) quinolinone 3] phenylaminomethyl phosphonate ester as cancer therapy drug application | 湖南大学 | 2017-10-24 | — | — | CN | disclosed |
| CN-105646579-A | Application of [2-(1H)-quinolinone-3-yl]phenylamino methylphosphonate as anti-cancer drug | 湖南大学 | 2016-06-08 | — | — | CN | disclosed |