Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1816298 | 0.82 | MAPT (0.41) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL845361 | 0.79 | ALDH1A1 (0.40) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL845299 | 0.78 | ALDH1A1 (0.42) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL900124 | 0.76 | MAPT (0.70) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18812444 | 0.75 | PDE4D (0.32) | — | |
| SCHEMBL28251463 | 0.73 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2794847 | 0.72 | MAPT (0.51) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28501406 | 0.71 | ALDH1A1 (0.44) | MAPTALDH1A1SMN1; SMN2GAACYP3A4 | |
| SCHEMBL15551711 | 0.70 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28807501 | 0.70 | SMN1; SMN2 (0.41) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646637-A | Abiraterone derivative, preparation method and medical applications thereof | 四川海思科制药有限公司 | 2016-06-08 | — | — | CN | disclosed |