Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27832699 | 0.77 | ALDH1A1 (0.37) | ALDH1A1TDP1LMNASMN1; SMN2GFER | |
| SCHEMBL14726457 | 0.77 | HDAC3 (0.32) | MAPT | |
| SCHEMBL28332880 | 0.76 | — | — | |
| SCHEMBL325134 | 0.75 | PKM (0.46) | ALDH1A1TDP1LMNASMN1; SMN2MAPT | |
| SCHEMBL14972833 | 0.75 | MAPT (0.51) | ALDH1A1SMN1; SMN2MAPTKMT2ANPC1 | |
| SCHEMBL11318891 | 0.75 | — | — | |
| SCHEMBL28659624 | 0.68 | KCNH2 (0.40) | LMNA | |
| SCHEMBL323777 | 0.68 | NOS1 (0.36) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL27917428 | 0.68 | HSD17B10 (0.58) | ALDH1A1TDP1LMNASMN1; SMN2GFER | |
| SCHEMBL11490688 | 0.66 | ALDH1A1 (0.35) | ALDH1A1TDP1LMNASMN1; SMN2GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104080781-B | 1H-indazole-3-benzamide compound is as the purposes of glycogen synthase kinase 3-beta inhibitors | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2016-05-11 | — | — | CN | disclosed |