Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 8/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL3410120 | 0.89 | NOS2 (0.37) | KCNH2NOS2GNAI3GNAO1GNAI1 | |
| Ethane SCHEMBL5466968 | 0.88 | — | — | |
| SCHEMBL62516 | 0.87 | — | — | |
| Methyl Alcohol SCHEMBL28212267 | 0.85 | — | — | |
| Diethylamine SCHEMBL27891136 | 0.85 | KCNH2 (0.40) | KCNH2NOS2GNAI3GNAO1GNAI1 | |
| Propanol SCHEMBL28967764 | 0.85 | GNAI3 (0.36) | KCNH2NOS2GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL5507781 | 0.84 | — | — | |
| Piperazine SCHEMBL27502392 | 0.84 | MAPT (0.43) | NOS2GABRA5GABRB2GABRPGABRD | |
| Hydrochloric Acid SCHEMBL1924289 | 0.84 | — | — | |
| Methane SCHEMBL27446706 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105593224-A | Novel quinazolinones as bromodomain inhibitors | ZENITH EPIGENETICS CORP | 2016-05-18 | — | — | CN | disclosed |