Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propanol SCHEMBL28967764 | 0.90 | GNAI3 (0.36) | NOS2GNAI3GNAO1GNAI1GABRA5 | |
| Propane SCHEMBL28065358 | 0.89 | KCNH2 (0.36) | NOS2GNAI3GNAO1GNAI1GABRA5 | |
| Methyl Alcohol SCHEMBL28212267 | 0.86 | — | — | |
| Ethane SCHEMBL5466968 | 0.83 | — | — | |
| Alcohol SCHEMBL27543257 | 0.83 | — | — | |
| SCHEMBL62516 | 0.83 | — | — | |
| Propionic Acid SCHEMBL27493235 | 0.81 | GABRA5 (0.45) | GNAI3GNAO1GNAI1GABRA5GABRB2 | |
| Diethylamine SCHEMBL27891136 | 0.80 | KCNH2 (0.40) | NOS2GNAI3GNAO1GNAI1GABRA5 | |
| Hydrochloric Acid SCHEMBL5507781 | 0.80 | — | — | |
| Alcohol SCHEMBL28440813 | 0.80 | ALDH1A1 (0.43) | GNAI3GNAO1GNAI1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699546-B1 | GAS CAPTURE PROCESS | COMMONWEALTH SCIENT & INDUSTRIAL RESEARCH ORGANISATION (AU) | 2019-06-26 | — | — | EP | disclosed |
| US-9409122-B2 | Gas capture process | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-08-09 | — | — | US | disclosed |
| CN-103619816-B | Gas trapping method | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-05-18 | — | — | CN | disclosed |
| US-20140127103-A1 | GAS CAPTURE PROCESS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2014-05-08 | — | — | US | disclosed |
| CN-103619816-A | Gas capture process | COMMW SCIENT IND RES ORG | 2014-03-05 | — | — | CN | disclosed |
| EP-2699546-A1 | GAS CAPTURE PROCESS | Commonwealth Scientific & Industrial Research Organisation (AU) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012142668-A1 | GAS CAPTURE PROCESS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-10-26 | — | — | WO | disclosed |
| US-8183380-B2 | 2-aminoquinolines | HOFFMANN-LA ROCHE INC. (US) | 2012-05-22 | — | — | US | disclosed |
| CN-101959876-A | 2-aminoquinolines | HOFFMANN LA ROCHE | 2011-01-26 | — | — | CN | disclosed |
| EP-2262789-A1 | 2-AMINOQUINOLINES | F. Hoffmann-La Roche AG (CH) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009109477-A1 | 2-AMINOQUINOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-11 | — | — | WO | disclosed |
| US-20090227570-A1 | 2-AMINOQUINOLINES | HOFFMANN-LA ROCHE, INC. | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227570-A1 | 2-AMINOQUINOLINES | HTR5A, HTR2C, HTR2A | NOS2 714/4885GNAI3 694/4885GNAO1 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.