Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28003519 | 0.86 | ACHE (0.34) | ACHE | |
| SCHEMBL30485646 | 0.86 | ACHE (0.34) | ACHE | |
| SCHEMBL23235450 | 0.67 | MEN1 (0.38) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL30499584 | 0.67 | MEN1 (0.38) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL2233984 | 0.67 | MAPT (0.38) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7024853 | 0.66 | PEPD (0.34) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL4621390 | 0.66 | CDC25B (0.55) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL21834864 | 0.66 | DRD2 (0.33) | MAPTRAB9AACHE | |
| SCHEMBL6711585 | 0.66 | MEN1 (0.37) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL28363963 | 0.65 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610271-B | 12-(2-fluorophenyl)-benzo [h] [1,3] methylene-dioxy [4,5-b] acridine-10,11-diketone and synthetic method thereof | XINXIANG UNIVERSITY (CN) | 2016-05-11 | — | — | CN | disclosed |