Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9109099 | 0.99 | PEPD (0.33) | PEPDALDH1A1HTR1AHTR7NPC1 | |
| SCHEMBL30485646 | 0.71 | ACHE (0.34) | — | |
| SCHEMBL28003519 | 0.71 | ACHE (0.34) | — | |
| SCHEMBL28065389 | 0.66 | MEN1 (0.36) | ALDH1A1MAPTHSD17B10MEN1LMNA | |
| SCHEMBL5205748 | 0.62 | NPC1 (0.63) | ALDH1A1NPC1MAPTGAAMEN1 | |
| SCHEMBL22321742 | 0.61 | TERT (0.61) | ALDH1A1NPC1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8884002 | 0.60 | NPC1 (0.61) | ALDH1A1NPC1MAPTGAAMEN1 | |
| SCHEMBL5062623 | 0.60 | PEPD (0.80) | PEPDALDH1A1NPC1MAPTGAA | |
| SCHEMBL7837810 | 0.59 | BAZ2B (0.73) | — | |
| SCHEMBL11906514 | 0.58 | PARP10 (0.56) | HTR1AHTR7DRD3AKT2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674621-B1 | ENANTIOMERS OF CARBAZOLE DERIVATIVES AS 5-HT1-LIKE AGONISTS | VERNALIS LTD (GB) | 2003-02-26 | — | — | EP | claimed |