Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13837823 | 0.80 | ALDH1A1 (0.58) | MAPTPOLBGAAKDM4ESMN1; SMN2 | |
| SCHEMBL418864 | 0.74 | SERPINE1 (0.48) | MAPTPOLBTP53GAAGFER | |
| SCHEMBL3193754 | 0.71 | MAPT (0.48) | MAPTPOLBTP53GAAGFER | |
| SCHEMBL21612947 | 0.71 | ALDH1A1 (0.61) | MAPTPOLBTP53GAAALDH1A1 | |
| SCHEMBL5430188 | 0.70 | ALDH1A1 (0.55) | MAPTPOLBTP53GAAKDM4E | |
| SCHEMBL6316142 | 0.69 | KDM4E (0.47) | MAPTPOLBTP53GAAGFER | |
| SCHEMBL1800640 | 0.68 | ALDH1A1 (0.72) | MAPTGAAKDM4ESMN1; SMN2ALDH1A1 | |
| Cyclohexane SCHEMBL7825607 | 0.67 | ABCC1 (0.57) | MAPTPOLBTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL5851124 | 0.67 | ALDH1A1 (0.78) | MAPTPOLBGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL27490522 | 0.67 | KDM4E (0.52) | MAPTGAAKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104013616-B | Amide groups-thiophenes is in the application of preparing in anti-HIV-1 virus drugs | Guangzhou Zhongheng Electronic Technology Co.,Ltd. (CN) | 2016-05-18 | — | — | CN | disclosed |
| CN-104013616-B | Amide groups-thiophenes is in the application of preparing in anti-HIV-1 virus drugs | Guangzhou Zhongheng Electronic Technology Co.,Ltd. (CN) | 2016-05-18 | — | — | CN | disclosed |