Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21612947 | 0.95 | ALDH1A1 (0.61) | ABCC1ALDH1A1MAPTPOLBGRIN2C | |
| SCHEMBL11324603 | 0.79 | AIP (0.66) | ALDH1A1MAPTPOLBGRIN2CKMT2A | |
| SCHEMBL2807303 | 0.79 | ALDH1A1 (0.60) | ABCC1ALDH1A1MAPTPOLBGRIN2C | |
| SCHEMBL8290785 | 0.77 | ALDH1A1 (0.58) | ABCC1ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL7825608 | 0.76 | ALDH1A1 (0.61) | ABCC1ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL23413214 | 0.76 | GRIN2C (0.58) | ABCC1ALDH1A1MAPTPOLBGRIN2C | |
| SCHEMBL5851124 | 0.76 | ALDH1A1 (0.78) | ALDH1A1MAPTPOLBKMT2AMAPK1 | |
| SCHEMBL11356974 | 0.73 | ALDH1A1 (0.75) | ALDH1A1MAPTPOLBKMT2AMAPK1 | |
| SCHEMBL3745498 | 0.73 | ABCC1 (0.51) | ABCC1ALDH1A1MAPTPOLBGRIN2C | |
| SCHEMBL20541663 | 0.72 | ALDH1A1 (0.74) | ABCC1ALDH1A1MAPTGRIN2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |