Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11189958 | 0.75 | PKM (0.43) | MAPTGAAGFERPKMALDH1A1 | |
| SCHEMBL13833660 | 0.73 | MAPT (0.66) | MAPTGAASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL28471303 | 0.72 | TOP2A (0.48) | MAPTGAAGFERPKMALDH1A1 | |
| SCHEMBL8329259 | 0.72 | ABCC1 (0.63) | MAPTGAAPKMALDH1A1MAPK1 | |
| SCHEMBL28065441 | 0.71 | MAPT (0.47) | MAPTGAAGFERALDH1A1SMN1; SMN2 | |
| SCHEMBL29273210 | 0.71 | L3MBTL1 (0.42) | MAPTGAAPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL4059329 | 0.70 | ABCC1 (0.50) | MAPTGAAGFERPKMALDH1A1 | |
| SCHEMBL6654580 | 0.70 | LMNA (0.63) | MAPTGAAPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL6249721 | 0.70 | GAA (0.47) | MAPTGAAPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL7244186 | 0.69 | FABP4 (0.46) | MAPTGAASMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486986-B2 | Microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-16 | — | — | US | disclosed |
| US-8202894-B2 | Microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2012-06-19 | — | — | US | disclosed |
| US-20100227898-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-20100222389-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-02 | — | — | US | disclosed |
| EP-2170858-A2 | NOVEL MICROBIOCIDES | Syngeta Participations AG (CH) | 2010-04-07 | — | — | EP | disclosed |
| EP-2167486-A2 | NOVEL MICROBIOCIDES | Syngeta Participations AG (CH) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009003672-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-01-08 | — | — | WO | disclosed |
| WO-2008151828-A2 | NOVEL MICROBIOCIDES | SYNGETA PARTICIPATIONS AG (CH) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227898-A1 | NOVEL MICROBIOCIDES | FPR1, CD14, MSR1 | MAPT 4783/4885GAA 1449/4885GFER 2144/4885 |
| US-20100222389-A1 | NOVEL MICROBIOCIDES | CD14, FPR1, MPO | MAPT 4756/4885GAA 1358/4885GFER 2143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.