Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960586 | 0.85 | ADRA2A (0.49) | ADRA2ACYP1A2CYP2A6CYP2D6CYP2C19 | |
| SCHEMBL17288369 | 0.82 | ADRA2A (0.47) | ADRA2ACYP1A2CYP2A6CYP2D6CYP2C19 | |
| SCHEMBL27749616 | 0.79 | CYP1A2 (0.53) | CYP1A2CYP2A6TDP1CYP2D6CYP2C19 | |
| SCHEMBL27320935 | 0.78 | ADRA2A (0.49) | ADRA2ACYP1A2CYP2A6TRPV1 | |
| SCHEMBL15345416 | 0.78 | ADRA2A (0.49) | ADRA2ACYP1A2CYP2A6PNMTTAAR1 | |
| SCHEMBL17288545 | 0.78 | ADRA2A (0.49) | ADRA2ACYP1A2CYP2A6CYP2D6CYP2C19 | |
| SCHEMBL27708845 | 0.75 | CA1 (0.41) | CYP1A2TDP1CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL27537674 | 0.74 | ALDH1A1 (0.50) | CYP1A2CYP2A6TDP1CYP2D6CYP2C19 | |
| SCHEMBL15715951 | 0.74 | ADRA2A (0.46) | ADRA2ACYP1A2CYP2A6TRPV1 | |
| SCHEMBL11619289 | 0.74 | ADRA2A (0.46) | ADRA2ACYP1A2CYP2A6CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183711-B | A kind of two-triaryl amine replaces phosphine oxygen base Benzophenanthrene compound, intermediate and preparation method and application | WEIXINNUO DISPLAY TECH CO., LTD. (CN) | 2016-04-20 | — | — | CN | disclosed |