Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460838 | 0.92 | DPP4 (0.43) | DPP4F2TAAR1HTR2AEPHX1 | |
| SCHEMBL915178 | 0.80 | DPP4 (0.47) | DPP4F2TAAR1HTR2ALMNA | |
| SCHEMBL6349748 | 0.77 | ADRA2A (0.54) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL7670364 | 0.76 | PGK1 (0.35) | — | |
| SCHEMBL3676574 | 0.76 | DPP4 (0.52) | DPP4F2TAAR1HTR2AADRA2A | |
| SCHEMBL15199514 | 0.76 | TAAR1 (0.44) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL10338130 | 0.76 | TAAR1 (0.42) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL28548590 | 0.76 | DPP4 (0.52) | DPP4F2TAAR1HTR2AADRA2A | |
| SCHEMBL11783322 | 0.72 | TAAR1 (0.41) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL28456091 | 0.72 | ADRB2 (0.52) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585583-A | Non-peptide IAP (inhibitor of apoptosis protein) antagonist as well as synthetic method and application thereof | UNIV GUANGDONG TECHNOLOGY | 2016-05-18 | — | — | CN | claimed |
| CN-105566447-A | Peptoid antagonist of anti-apoptosis protein and synthesis method and application of peptoid antagonist | UNIV GUANGDONG TECHNOLOGY | 2016-05-11 | — | — | CN | claimed |
| CN-105566447-B | The class peptide antagonists and its synthetic method of a kind of apoptosis inhibitory protein and application | 广东工业大学 | 2019-09-20 | — | — | CN | disclosed |
| CN-105585583-A | Non-peptide IAP (inhibitor of apoptosis protein) antagonist as well as synthetic method and application thereof | UNIV GUANGDONG TECHNOLOGY | 2016-05-18 | — | — | CN | disclosed |
| CN-105566447-A | Peptoid antagonist of anti-apoptosis protein and synthesis method and application of peptoid antagonist | UNIV GUANGDONG TECHNOLOGY | 2016-05-11 | — | — | CN | disclosed |