Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 5/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19289759 | 0.85 | HSD17B10 (0.45) | HSD17B10CAMK2ABACE1CYP3A4 | |
| SCHEMBL157921 | 0.82 | IDO1 (0.50) | P2RX7CYP3A4ERCC1ERCC4 | |
| SCHEMBL29712851 | 0.82 | IDO1 (0.50) | P2RX7CYP3A4ERCC1ERCC4 | |
| SCHEMBL2238912 | 0.82 | CAMK2A (0.59) | HSD17B10CAMK2A | |
| SCHEMBL5724002 | 0.81 | CA2 (0.48) | HSD17B10CAMK2ABACE1P2RX7CYP3A4 | |
| SCHEMBL28729688 | 0.81 | HSD17B10 (0.45) | HSD17B10CAMK2ATTR | |
| SCHEMBL29595425 | 0.81 | HSD17B10 (0.45) | HSD17B10CAMK2ATTR | |
| SCHEMBL4711040 | 0.80 | ALDH1A1 (0.51) | HSD17B10CAMK2ABACE1P2RX7 | |
| SCHEMBL30581858 | 0.80 | ALDH1A1 (0.51) | HSD17B10CAMK2ABACE1P2RX7 | |
| SCHEMBL4709927 | 0.80 | P2RX7 (0.48) | HSD17B10CAMK2ABACE1P2RX7ERCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103796992-B | Guanidinobenzoic acid compound | ASTELLAS PHARMA INC. (JP) | 2016-04-27 | — | — | CN | disclosed |